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ADAM7 - Riwayat revisi
2026-09-16T04:02:00Z
Riwayat revisi halaman ini di wiki
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Maintenance script: Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi
2026-08-28T18:12:35Z
<p>Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Revisi sebelumnya</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revisi per 28 Agustus 2026 18.12</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5">Baris 5:</td>
<td colspan="2" class="diff-lineno">Baris 5:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Pranala luar ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Pranala luar ==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* The [[MEROPS]] online database for peptidases and their inhibitors: [http://merops.sanger.ac.uk/cgi-bin/merops.cgi?id=M12.956 M12.956]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* The [[MEROPS]] online database for peptidases and their inhibitors: [http://merops.sanger.ac.uk/cgi-bin/merops.cgi?id=M12.956 M12.956]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*[http://endo.endojournals.org/cgi/content/full/138/10/4262 Endocrinology Journal]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*[http://endo.endojournals.org/cgi/content/full/138/10/4262 Endocrinology Journal] </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Gene expression/activity chart via biogps: [http://biogps.org/#goto=genereport&id=8756 mRNA Tissue Expression]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Gene expression/activity chart via biogps: [http://biogps.org/#goto=genereport&id=8756 mRNA Tissue Expression]</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Sumber dan atribusi ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Sumber dan atribusi ==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=ADAM7&oldid=29526925 Wikipedia bahasa Indonesia], revisi 29526925 (2026-08-05T02:01:51Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=ADAM7&oldid=29526925 Wikipedia bahasa Indonesia], revisi 29526925 (2026-08-05T02:01:51Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div></td></tr>
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https://wiki.unissula.ac.id/index.php?title=ADAM7&diff=23245&oldid=prev
Maintenance script: Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 29526925; atribusi sumber disertakan.
2026-08-28T17:48:20Z
<p>Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 29526925; atribusi sumber disertakan.</p>
<p><b>Halaman baru</b></p><div>'''ADAM7''' (''Disintegrin and metalloproteinase domain-containing protein 7''; protein yang mengandung domain disintegrin dan metaloproteinase 7) adalah suatu [[protein]] yang dihasilkan dari ekspresi gen ADAM7 pada manusia. ADAM7 merupakan [[enzim]] dengan massa molekul sekitar 85 kDa yang termasuk dalam famili protein transmembran [[ADAM]] (''A Disintegrin and Metalloproteinase''). Anggota famili ini merupakan protein yang tertambat pada membran dan secara struktural berkerabat dengan [[disintegrin]] pada bisa [[ular]]. Protein-protein tersebut berperan dalam berbagai proses biologis yang melibatkan interaksi antarsel maupun interaksi antara sel dan [[matriks ekstraseluler]], termasuk pembuahan, perkembangan otot, dan neurogenesis. ADAM7 berperan penting dalam pematangan [[spermatozoa]] pada [[mamalia]]. ADAM7 juga dikenal dengan beberapa nama lain, yaitu '''ADAM_7''', '''ADAM-7''', '''EAPI''', '''GP-83''', dan '''GP83'''.<br />
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== Fungsi ==<br />
Fungsi ADAM7 berkaitan erat dengan pematangan [[spermatozoa]] dan proses pembuahan. Spermatozoa tidak dapat bergerak hingga melewati [[epididimis]], tempat spermatozoa berinteraksi dengan berbagai protein yang disekresikan oleh sel-sel epitel epididimis. Karena tidak memiliki aktivitas [[protease]], ADAM7 diduga berperan dalam interaksi antarprotein dan proses adhesi sel, termasuk fusi antara spermatozoa dan sel telur. ADAM7 disekresikan oleh sel-sel [[epididimis]] dan kemudian dipindahkan ke permukaan spermatozoa yang sedang mengalami pematangan. Berdasarkan penelitian knockout gen pada tikus, jumlah ADAM7 yang disekresikan berhubungan langsung dengan kadar protein [[ADAM2]] dan [[ADAM3]]. Pembentukan kompleks antara ADAM7, [[kalneksin]] (Calnexin), [[HSPA5]], dan [[ITM2B]] diketahui berfungsi sebagai pendamping molekuler (molecular chaperone) setelah ADAM7 terintegrasi ke dalam membran spermatozoa. Selain itu, pembentukan kompleks dengan ITM2B meningkat selama proses [[kapasitasi]] spermatozoa, yang mengakibatkan perubahan konformasi pada ADAM7. Dengan demikian, ADAM7 memiliki peran penting dalam proses kapasitasi spermatozoa, meskipun mekanisme fungsinya hingga kini masih belum sepenuhnya dipahami.<br />
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== Pranala luar ==<br />
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* The [[MEROPS]] online database for peptidases and their inhibitors: [http://merops.sanger.ac.uk/cgi-bin/merops.cgi?id=M12.956 M12.956]<br />
*[http://endo.endojournals.org/cgi/content/full/138/10/4262 Endocrinology Journal]<br />
* Gene expression/activity chart via biogps: [http://biogps.org/#goto=genereport&id=8756 mRNA Tissue Expression]<br />
*<br />
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== Sumber dan atribusi ==<br />
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Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=ADAM7&oldid=29526925 Wikipedia bahasa Indonesia], revisi 29526925 (2026-08-05T02:01:51Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div>
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