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Faktor PTA - Riwayat revisi
2026-09-16T09:06:23Z
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Maintenance script: Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi
2026-08-29T14:01:51Z
<p>Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Revisi sebelumnya</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revisi per 29 Agustus 2026 14.01</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Baris 1:</td>
<td colspan="2" class="diff-lineno">Baris 1:</td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">'''Faktor PTA''' atau '''faktor XI''' () adalah </del>[[<del style="font-weight: bold; text-decoration: none;">zimogen]] dari jenis [[serina protease]] yang merupakan prekursor dari [[faktor XIa]], yang disekresi ke dalam sirkulasi darah untuk mengaktivasi plasma [[tromboplastin]] intrinsik saat darah terpapar oleh permukaan asing</del>. <del style="font-weight: bold; text-decoration: none;">Pada [[manusia</del>]]<del style="font-weight: bold; text-decoration: none;">, FXI terkodikasi dalam [[gen]] F11.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[<ins style="font-weight: bold; text-decoration: none;">File:Protein_F11_PDB_1xx9</ins>.<ins style="font-weight: bold; text-decoration: none;">png|thumb|right|280px|Protein F11 PDB 1xx9</ins>]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">FXI disintesis oleh </del>[[<del style="font-weight: bold; text-decoration: none;">hati</del>]] <del style="font-weight: bold; text-decoration: none;">dan </del>disekresi dalam <del style="font-weight: bold; text-decoration: none;">bentuk </del>[[<del style="font-weight: bold; text-decoration: none;">dimer|homo</del>-<del style="font-weight: bold; text-decoration: none;">dimer</del>]] <del style="font-weight: bold; text-decoration: none;">yang tidak aktif dengan </del>[[<del style="font-weight: bold; text-decoration: none;">waktu paruh</del>]] <del style="font-weight: bold; text-decoration: none;">sekitar </del>52 <del style="font-weight: bold; text-decoration: none;">jam dan rasio plasma sekitar </del>5 <del style="font-weight: bold; text-decoration: none;">mcg</del>/<del style="font-weight: bold; text-decoration: none;">mL.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">'''Faktor PTA''' atau '''faktor XI''' () adalah [[zimogen]] dari jenis [[serina protease]] yang merupakan prekursor dari </ins>[[<ins style="font-weight: bold; text-decoration: none;">faktor XIa</ins>]]<ins style="font-weight: bold; text-decoration: none;">, yang </ins>disekresi <ins style="font-weight: bold; text-decoration: none;">ke </ins>dalam <ins style="font-weight: bold; text-decoration: none;">sirkulasi darah untuk mengaktivasi plasma </ins>[[<ins style="font-weight: bold; text-decoration: none;">tromboplastin]] intrinsik<ref>[http://medical-dictionary.thefreedictionary.com/factor+VI Factors]. ''Farlex free dictionary''.</ref> saat darah terpapar oleh permukaan asing.<ref>[http://www.answers.com/topic/factor</ins>-<ins style="font-weight: bold; text-decoration: none;">xi Factor XI]. ''Answer.com''.</ref> Pada [[manusia</ins>]]<ins style="font-weight: bold; text-decoration: none;">, FXI terkodikasi dalam </ins>[[<ins style="font-weight: bold; text-decoration: none;">gen</ins>]] <ins style="font-weight: bold; text-decoration: none;">F11.<ref>Fujikawa K, Chung DW, Hendrickson LE, Davie EW. ''Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein''. ''Biochemistry''. 1986. Vol. 25 (9). hlm. 2417–24. doi:10.1021/bi00357a018.</ref><ref>Asakai R, Davie EW, Chung DW. ''Organization of the gene for human factor XI''. ''Biochemistry''. 1987. Vol. 26 (23). hlm. 7221–8. doi:10.1021/bi00397a004.</ref><ref>Kato A, Asakai R, Davie EW, Aoki N. ''Factor XI gene (F11) is located on the distal end of the long arm of human chromosome 4''. ''Cytogenet. Cell Genet''. 1989. Vol. </ins>52 <ins style="font-weight: bold; text-decoration: none;">(1-2). hlm. 77–8. doi:10.1159/000132844.</ref><ref>Buetow KH, Shiang R, Yang P, Nakamura Y, Lathrop GM, White R, Wasmuth JJ, Wood S, Berdahl LD, Leysens NJ. ''A detailed multipoint map of human chromosome 4 provides evidence for linkage heterogeneity and position-specific recombination rates''. ''Am. J. Hum. Genet''. 1991. Vol. 48 (</ins>5<ins style="font-weight: bold; text-decoration: none;">). hlm. 911–25.<</ins>/<ins style="font-weight: bold; text-decoration: none;">ref></ins></div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">== Rujukan ==</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">FXI disintesis oleh [[hati]] dan disekresi dalam bentuk [[dimer|homo-dimer]] yang tidak aktif<ref>Wu W, Sinha D, Shikov S, Yip CK, Walz T, Billings PC, Lear JD, Walsh PN. ''Factor XI homodimer structure is essential for normal proteolytic activation by factor XIIa, thrombin, and factor XIa''. ''J. Biol. Chem''. 2008. Vol. 283 (27). hlm. 18655–64. doi:10.1074/jbc.M802275200.</ref> dengan [[waktu paruh]] sekitar 52 jam dan rasio plasma sekitar 5 mcg/mL.<ref>[http://emedicine.medscape.com/article/209984-overview Factor XI Deficiency]. ''Cardeza Foundation Hemophilia Treatment Center, Thomas Jefferson University; Jamie E Siegel''.</ref></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Pranala luar ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Pranala luar ==</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l12">Baris 12:</td>
<td colspan="2" class="diff-lineno">Baris 11:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [http://content.nejm.org/cgi/content/full/342/10/696 High Levels of Coagulation Factor XI as a Risk Factor for Venous Thrombosis] . New England Journal of Medicine; Joost C.M. Meijers, Winnie L.H. Tekelenburg, et al.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [http://content.nejm.org/cgi/content/full/342/10/696 High Levels of Coagulation Factor XI as a Risk Factor for Venous Thrombosis] . New England Journal of Medicine; Joost C.M. Meijers, Winnie L.H. Tekelenburg, et al.</div></td></tr>
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<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Referensi ==</ins></div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Sumber dan atribusi ==</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del style="font-weight: bold; text-decoration: none;">Sumber </del>dan <del style="font-weight: bold; text-decoration: none;">atribusi ==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title</ins>=<ins style="font-weight: bold; text-decoration: none;">Faktor+PTA&oldid</ins>=<ins style="font-weight: bold; text-decoration: none;">29600462 Wikipedia bahasa Indonesia], revisi 29600462 (2026-08-19T13:35:03Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Gambar pada artikel ini bersumber dari Wikimedia Commons </ins>dan <ins style="font-weight: bold; text-decoration: none;">mengikuti ketentuan lisensi masing-masing berkas. Mohon gunakan konten dan media secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Faktor+PTA&oldid=29600462 Wikipedia bahasa Indonesia], revisi 29600462 (2026</del>-<del style="font-weight: bold; text-decoration: none;">08</del>-<del style="font-weight: bold; text-decoration: none;">19T13:35:03Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi</del>-<del style="font-weight: bold; text-decoration: none;">BerbagiSerupa (CC BY</del>-<del style="font-weight: bold; text-decoration: none;">SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><!</ins>-- <ins style="font-weight: bold; text-decoration: none;">WIKI_UNISSULA_PRESENTATION_V4 </ins>--<ins style="font-weight: bold; text-decoration: none;">></ins></div></td></tr>
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Maintenance script: Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 29600462; atribusi sumber disertakan.
2026-08-29T13:25:11Z
<p>Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 29600462; atribusi sumber disertakan.</p>
<p><b>Halaman baru</b></p><div>'''Faktor PTA''' atau '''faktor XI''' () adalah [[zimogen]] dari jenis [[serina protease]] yang merupakan prekursor dari [[faktor XIa]], yang disekresi ke dalam sirkulasi darah untuk mengaktivasi plasma [[tromboplastin]] intrinsik saat darah terpapar oleh permukaan asing. Pada [[manusia]], FXI terkodikasi dalam [[gen]] F11.<br />
<br />
FXI disintesis oleh [[hati]] dan disekresi dalam bentuk [[dimer|homo-dimer]] yang tidak aktif dengan [[waktu paruh]] sekitar 52 jam dan rasio plasma sekitar 5 mcg/mL.<br />
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== Rujukan ==<br />
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== Pranala luar ==<br />
* [http://peir.path.uab.edu/coag UAB Coagulation Service] . Department of Pathology, UAB Hospital.<br />
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== Bacaan lanjut ==<br />
* [http://content.nejm.org/cgi/content/full/342/10/696 High Levels of Coagulation Factor XI as a Risk Factor for Venous Thrombosis] . New England Journal of Medicine; Joost C.M. Meijers, Winnie L.H. Tekelenburg, et al.<br />
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== Sumber dan atribusi ==<br />
<br />
Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Faktor+PTA&oldid=29600462 Wikipedia bahasa Indonesia], revisi 29600462 (2026-08-19T13:35:03Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div>
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