https://wiki.unissula.ac.id/index.php?action=history&feed=atom&title=Faktor_pertumbuhan_hepatosit 2026-09-15T13:19:10Z Riwayat revisi halaman ini di wiki MediaWiki 1.46.0 https://wiki.unissula.ac.id/index.php?title=Faktor_pertumbuhan_hepatosit&diff=26580&oldid=prev 2026-08-29T14:00:56Z

<p>Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi</p> <table style="background-color: #fff; color: #202122;" data-mw-interface=""> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="id"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Revisi sebelumnya</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revisi per 29 Agustus 2026 14.00</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Baris 1:</td> <td colspan="2" class="diff-lineno">Baris 1:</td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Faktor pertumbuhan hepatosit''' () adalah [[sitokina]] hasil [[sekresi]] [[sel mesenkimal]] yang memiliki multi-fungsi antara lain berperan dalam perkembangan [[sel (biologi)|sel]], [[motilitas]], [[morfogenesis]] pada lintasan [[tirosina kinase]], sehingga mempunyai peran penting dalam [[angiogenesis]], [[tumorogenesis]] dan perbaikan [[jaringan]] [[tubuh]].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[[File:Protein_HGF_PDB_1bht.png|thumb|right|280px|Protein HGF PDB 1bht]]</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Faktor pertumbuhan hepatosit''' () adalah [[sitokina]] hasil [[sekresi]] [[sel mesenkimal]] yang memiliki multi-fungsi antara lain berperan dalam perkembangan [[sel (biologi)|sel]], [[motilitas]], [[morfogenesis]] pada lintasan [[tirosina kinase]], sehingga mempunyai peran penting dalam [[angiogenesis]], [[tumorogenesis]] dan perbaikan [[jaringan]] [[tubuh]].<ins style="font-weight: bold; text-decoration: none;">&lt;ref&gt;[http://www.ncbi.nlm.nih.gov/sites/gene/3082 HGF hepatocyte growth factor (hepapoietin A; scatter factor) [ Homo sapiens ]]. ''Entrez Gene''.&lt;/ref&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>HGF disekresi sebagai [[polipeptida]] yang tidak aktif dan kemudian teriris oleh [[serina protease]] menjadi rantai alfa dengan [[massa]] 69 [[satuan massa atom|kDa]] dan rantai beta dengan massa 34 kDa.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>HGF disekresi sebagai [[polipeptida]] yang tidak aktif dan kemudian teriris oleh [[serina protease]] menjadi rantai alfa dengan [[massa]] 69 [[satuan massa atom|kDa]] dan rantai beta dengan massa 34 kDa.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Rendahnya rasio HGF di dalam [[plasma darah]] dianggap merupakan pemicu terjadinya [[hepatitis]] kronis, karena pengaruh HGF yang bersifat anti-[[apoptosis|apoptotik]], anti-[[radang]] terhadap [[hepatosit]]. Rasio HGF yang rendah, dapat ditingkatkan oleh induksi [[asam maleat]], atau dengan asupan [[buah]] [[peria|Momordica charantia L.]] secara teratur. [[Sekresi]] HGF juga dapat diinduksi oleh aktivasi [[protein kinase A]] dan [[protein kinase C]], [[Faktor pertumbuhan epidermal|EGF]], [[Faktor nekrosis tumor-alfa|TNF-α]], dan [[interferon|interferon-gamma]]. Efek yang diberikan oleh interferon-gamma, tidak dapat disubstitusi oleh interferon-alfa maupun interferon-beta.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Rendahnya rasio HGF di dalam [[plasma darah]] dianggap merupakan pemicu terjadinya [[hepatitis]] kronis, karena pengaruh HGF yang bersifat anti-[[apoptosis|apoptotik]], anti-[[radang]] terhadap [[hepatosit]].<ins style="font-weight: bold; text-decoration: none;">&lt;ref&gt;[http://www.ncbi.nlm.nih.gov/pubmed/17465748 Hepatocyte growth factor: a regenerative drug for acute hepatitis and liver cirrhosis]. ''Division of Molecular Regenerative Medicine, Department of Biochemistry and Molecular Biology, Osaka University Graduate School of Medicine; Mizuno S, Nakamura T''.&lt;/ref&gt;&lt;ref&gt;[http://www.ncbi.nlm.nih.gov/pubmed/15793283 Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis]. ''Division of Molecular Regenerative Medicine, Course of Advanced Medicine, Osaka University Graduate School of Medicine; Kim WH, Matsumoto K, Bessho K, Nakamura T''.&lt;/ref&gt; </ins>Rasio HGF yang rendah, dapat ditingkatkan oleh induksi [[asam maleat]],<ins style="font-weight: bold; text-decoration: none;">&lt;ref&gt;[http://www.ncbi.nlm.nih.gov/pubmed/18491380 Induction of hepatocyte growth factor expression by maleic acid in human fibroblasts through MAPK activation]. ''Department of Immunochemistry, Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; Motoki T, Sugiura Y, Matsumoto Y, Tsuji T, Kubota S, Takigawa M, Gohda E''.&lt;/ref&gt; </ins>atau dengan asupan [[buah]] [[peria|Momordica charantia L.]] secara teratur.<ins style="font-weight: bold; text-decoration: none;">&lt;ref&gt;[http://www.ncbi.nlm.nih.gov/pubmed/19223201 Induction of hepatocyte growth factor production in human dermal fibroblasts and their proliferation by the extract of bitter melon pulp]. ''Department of Immunochemistry, Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; Ono T, Tsuji T, Sakai M, Yukizaki C, Ino H, Akagi I, Hiramatsu K, Matsumoto Y, Sugiura Y, Uto H, Tsubouchi H, Gohda E''.&lt;/ref&gt; </ins>[[Sekresi]] HGF juga dapat diinduksi oleh aktivasi [[protein kinase A]] dan [[protein kinase C]], [[Faktor pertumbuhan epidermal|EGF]], [[Faktor nekrosis tumor-alfa|TNF-α]],<ins style="font-weight: bold; text-decoration: none;">&lt;ref&gt;[http://www.ncbi.nlm.nih.gov/pubmed/15541342 Inhibition of hepatocyte growth factor induction in human dermal fibroblasts by interleukin-1 and its prevention by interferon-gamma]. ''Department of Immunochemistry, Faculty of Pharmaceutical Sciences, Okayama University; Takami Y, Kanasaki K, Tsubouchi H, Ishii T, Yamamoto I, Gohda E''.&lt;/ref&gt; </ins>dan [[interferon|interferon-gamma]]. Efek yang diberikan oleh interferon-gamma, tidak dapat disubstitusi oleh interferon-alfa maupun interferon-beta.<ins style="font-weight: bold; text-decoration: none;">&lt;ref&gt;[http://www.ncbi.nlm.nih.gov/pubmed/15629451 Synergistic induction of hepatocyte growth factor in human skin fibroblasts by the inflammatory cytokines interleukin-1 and interferon-gamma]. ''Department of Immunochemistry, Faculty of Pharmaceutical Sciences, Okayama University; Takami Y, Motoki T, Yamamoto I, Gohda E''.&lt;/ref&gt;</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">== Rujukan ==</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Referensi ==</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;references /&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Sumber dan atribusi ==</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del style="font-weight: bold; text-decoration: none;">Sumber </del>dan <del style="font-weight: bold; text-decoration: none;">atribusi ==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title</ins>=<ins style="font-weight: bold; text-decoration: none;">Faktor+pertumbuhan+hepatosit&amp;oldid</ins>=<ins style="font-weight: bold; text-decoration: none;">26994140 Wikipedia bahasa Indonesia], revisi 26994140 (2025-03-04T16:50:48Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Gambar pada artikel ini bersumber dari Wikimedia Commons </ins>dan <ins style="font-weight: bold; text-decoration: none;">mengikuti ketentuan lisensi masing-masing berkas. Mohon gunakan konten dan media secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Faktor+pertumbuhan+hepatosit&amp;oldid=26994140 Wikipedia bahasa Indonesia], revisi 26994140 (2025</del>-<del style="font-weight: bold; text-decoration: none;">03</del>-<del style="font-weight: bold; text-decoration: none;">04T16:50:48Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi</del>-<del style="font-weight: bold; text-decoration: none;">BerbagiSerupa (CC BY</del>-<del style="font-weight: bold; text-decoration: none;">SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;!</ins>-- <ins style="font-weight: bold; text-decoration: none;">WIKI_UNISSULA_PRESENTATION_V4 </ins>--<ins style="font-weight: bold; text-decoration: none;">&gt;</ins></div></td></tr> </table>

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<p>Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 26994140; atribusi sumber disertakan.</p> <p><b>Halaman baru</b></p><div>&#039;&#039;&#039;Faktor pertumbuhan hepatosit&#039;&#039;&#039; () adalah [[sitokina]] hasil [[sekresi]] [[sel mesenkimal]] yang memiliki multi-fungsi antara lain berperan dalam perkembangan [[sel (biologi)|sel]], [[motilitas]], [[morfogenesis]] pada lintasan [[tirosina kinase]], sehingga mempunyai peran penting dalam [[angiogenesis]], [[tumorogenesis]] dan perbaikan [[jaringan]] [[tubuh]].<br /> <br /> HGF disekresi sebagai [[polipeptida]] yang tidak aktif dan kemudian teriris oleh [[serina protease]] menjadi rantai alfa dengan [[massa]] 69 [[satuan massa atom|kDa]] dan rantai beta dengan massa 34 kDa.<br /> <br /> Rendahnya rasio HGF di dalam [[plasma darah]] dianggap merupakan pemicu terjadinya [[hepatitis]] kronis, karena pengaruh HGF yang bersifat anti-[[apoptosis|apoptotik]], anti-[[radang]] terhadap [[hepatosit]]. Rasio HGF yang rendah, dapat ditingkatkan oleh induksi [[asam maleat]], atau dengan asupan [[buah]] [[peria|Momordica charantia L.]] secara teratur. [[Sekresi]] HGF juga dapat diinduksi oleh aktivasi [[protein kinase A]] dan [[protein kinase C]], [[Faktor pertumbuhan epidermal|EGF]], [[Faktor nekrosis tumor-alfa|TNF-α]], dan [[interferon|interferon-gamma]]. Efek yang diberikan oleh interferon-gamma, tidak dapat disubstitusi oleh interferon-alfa maupun interferon-beta.<br /> <br /> == Rujukan ==<br /> <br /> <br /> <br /> == Sumber dan atribusi ==<br /> <br /> Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Faktor+pertumbuhan+hepatosit&amp;oldid=26994140 Wikipedia bahasa Indonesia], revisi 26994140 (2025-03-04T16:50:48Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div>

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