https://wiki.unissula.ac.id/index.php?action=history&feed=atom&title=GLP-1
GLP-1 - Riwayat revisi
2026-09-16T12:56:11Z
Riwayat revisi halaman ini di wiki
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https://wiki.unissula.ac.id/index.php?title=GLP-1&diff=26884&oldid=prev
Maintenance script: Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi
2026-08-29T14:14:04Z
<p>Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Revisi sebelumnya</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revisi per 29 Agustus 2026 14.14</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5">Baris 5:</td>
<td colspan="2" class="diff-lineno">Baris 5:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>GLP-1 mempunyai [[waktu paruh]] kurang dari 2 [[menit]] oleh karena reaksi degradasi oleh [[enzim]] dipeptidil peptidase-4.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>GLP-1 mempunyai [[waktu paruh]] kurang dari 2 [[menit]] oleh karena reaksi degradasi oleh [[enzim]] dipeptidil peptidase-4.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>GLP-1 memiliki beberapa kapasitas fisiologis untuk menekan [[diabetes mellitus]], antara lain:</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>GLP-1 memiliki beberapa kapasitas fisiologis untuk menekan [[diabetes mellitus]],<ins style="font-weight: bold; text-decoration: none;"><ref>[http://www.medscape.com/viewprogram/3418_pnt "Diabetes and Intestinal Incretin Hormones: A New Therapeutic Paradigm" at medscape.com (slide 36)]</ref><ref>Toft-Nielsen M, Madsbad S, Holst J. ''Determinants of the effectiveness of glucagon-like peptide-1 in type 2 diabetes''. ''J Clin Endocrinol Metab''. 2001. Vol. 86 (8). hlm. 3853–60. doi:10.1210/jc.86.8.3853.</ref><ref>Meier J, Weyhe D, Michaely M, Senkal M, Zumtobel V, Nauck M, Holst J, Schmidt W, Gallwitz B. ''Intravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetes''. ''Crit Care Med''. 2004. Vol. 32 (3). hlm. 848–51. doi:10.1097/01.CCM.0000114811.60629.B5.</ref> </ins>antara lain:</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* membuat [[pankreas]] lebih reaktif terhadap [[glukosa]] darah dan meningkatkan sekresi [[insulin]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* membuat [[pankreas]] lebih reaktif terhadap [[glukosa]] darah dan meningkatkan sekresi [[insulin]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* menurunkan sekresi [[glukagon]] dari sel @ [[pankreas]].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* menurunkan sekresi [[glukagon]] dari sel @ [[pankreas]].</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l11">Baris 11:</td>
<td colspan="2" class="diff-lineno">Baris 11:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* menekan sekresi [[asam lambung]] dan kadar gas lambung.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* menekan sekresi [[asam lambung]] dan kadar gas lambung.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>== <ins style="font-weight: bold; text-decoration: none;">Referensi </ins>==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del style="font-weight: bold; text-decoration: none;">Rujukan </del>==</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><references /></ins></div></td></tr>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Sumber dan atribusi ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Sumber dan atribusi ==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=GLP-1&oldid=28558419 Wikipedia bahasa Indonesia], revisi 28558419 (2025-11-20T02:58:46Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=GLP-1&oldid=28558419 Wikipedia bahasa Indonesia], revisi 28558419 (2025-11-20T02:58:46Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div></td></tr>
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Maintenance script: Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 28558419; atribusi sumber disertakan.
2026-08-29T13:54:23Z
<p>Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 28558419; atribusi sumber disertakan.</p>
<p><b>Halaman baru</b></p><div>'''GLP-1''' () adalah [[hormon]] yang dihasilkan oleh [[sel L]] pada [[saluran pencernaan]] dari produk transkripsi [[gen]] [[proglukagon]], dan digolongkan sebagai [[inkretin]]. Seperti juga [[Glukagon]], GLP-1 mengalami [[proteolisis]] terbatas dalam proses sintesanya. Bentuk aktif dari hormon ini adalah GLP-1-(7-37) dan GLP-1-(7-36)NH2.<br />
<br />
Stimulus () untuk [[sekresi]] hormon ini adalah keberadaan zat nutrisi pada [[lumen]] [[usus halus]], khususnya [[karbohidrat]], [[protein]] dan [[lemak]].<br />
<br />
GLP-1 mempunyai [[waktu paruh]] kurang dari 2 [[menit]] oleh karena reaksi degradasi oleh [[enzim]] dipeptidil peptidase-4.<br />
<br />
GLP-1 memiliki beberapa kapasitas fisiologis untuk menekan [[diabetes mellitus]], antara lain:<br />
* membuat [[pankreas]] lebih reaktif terhadap [[glukosa]] darah dan meningkatkan sekresi [[insulin]]<br />
* menurunkan sekresi [[glukagon]] dari sel @ [[pankreas]].<br />
* meningkatkan massa [[sel beta|sel ß]] dan [[ekspresi gen]] insulin.<br />
* menekan sekresi [[asam lambung]] dan kadar gas lambung.<br />
<br />
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== Rujukan ==<br />
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<br />
<br />
== Sumber dan atribusi ==<br />
<br />
Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=GLP-1&oldid=28558419 Wikipedia bahasa Indonesia], revisi 28558419 (2025-11-20T02:58:46Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div>
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