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Perforin - Riwayat revisi
2026-09-16T21:57:06Z
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https://wiki.unissula.ac.id/index.php?title=Perforin&diff=26766&oldid=prev
Maintenance script: Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi
2026-08-29T14:09:14Z
<p>Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Revisi sebelumnya</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revisi per 29 Agustus 2026 14.09</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Baris 1:</td>
<td colspan="2" class="diff-lineno">Baris 1:</td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">'''Perforin''' () adalah </del>[[<del style="font-weight: bold; text-decoration: none;">sitokin]] berupa [[protein</del>]] <del style="font-weight: bold; text-decoration: none;">yang diekspresikan oleh [[gen]] PRF1.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[<ins style="font-weight: bold; text-decoration: none;">File:Plumacpf2.png|thumb|right|280px|Plumacpf2</ins>]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Perforin <del style="font-weight: bold; text-decoration: none;">dapat ditemukan pada </del>[[<del style="font-weight: bold; text-decoration: none;">granula|granul</del>]] [[<del style="font-weight: bold; text-decoration: none;">sel T</del>]] <del style="font-weight: bold; text-decoration: none;">CD8 dan </del>[[<del style="font-weight: bold; text-decoration: none;">sel NK</del>]]. <del style="font-weight: bold; text-decoration: none;">Setelah proses [[degranulasi]]</del>, <del style="font-weight: bold; text-decoration: none;">sekresi </del>perforin <del style="font-weight: bold; text-decoration: none;">akan tersisipkan pada </del>[<del style="font-weight: bold; text-decoration: none;">[membran sel]] dan membentuk sebuah lubang</del>. <del style="font-weight: bold; text-decoration: none;">Bagian </del>perforin <del style="font-weight: bold; text-decoration: none;">yang menancap pada membran tersebut adalah domain [[MACPF]</del>].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">'''</ins>Perforin<ins style="font-weight: bold; text-decoration: none;">''' () adalah </ins>[[<ins style="font-weight: bold; text-decoration: none;">sitokin</ins>]] <ins style="font-weight: bold; text-decoration: none;">berupa </ins>[[<ins style="font-weight: bold; text-decoration: none;">protein</ins>]] <ins style="font-weight: bold; text-decoration: none;">yang diekspresikan oleh </ins>[[<ins style="font-weight: bold; text-decoration: none;">gen</ins>]] <ins style="font-weight: bold; text-decoration: none;">PRF1.<ref>Fink TM, Zimmer M, Weitz S, Tschopp J, Jenne DE, Lichter P. ''Human perforin (PRF1) maps to 10q22, a region that is syntenic with mouse chromosome 10''. ''Genomics''. 1992. Vol. 13 (4). hlm. 1300–2</ins>.<ins style="font-weight: bold; text-decoration: none;"></ref><ref>Shinkai Y, Yoshida MC, Maeda K, Kobata T, Maruyama K, Yodoi J, Yagita H</ins>, <ins style="font-weight: bold; text-decoration: none;">Okumura K. ''Molecular cloning and chromosomal assignment of a human </ins>perforin <ins style="font-weight: bold; text-decoration: none;">(PFP) gene''. ''Immunogenetics''. 1990. Vol. 30 (6). hlm. 452–7.</ref><ref></ins>[<ins style="font-weight: bold; text-decoration: none;">http://www.ncbi.nlm.nih</ins>.<ins style="font-weight: bold; text-decoration: none;">gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5551 Entrez Gene: PRF1 </ins>perforin <ins style="font-weight: bold; text-decoration: none;">1 (pore forming protein)</ins>].<ins style="font-weight: bold; text-decoration: none;"></ref></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Perforin <del style="font-weight: bold; text-decoration: none;">bersinergi dengan ''membrane-attack complex'' (MAC) yang dilakukan protein </del>[[<del style="font-weight: bold; text-decoration: none;">komplemen</del>]] <del style="font-weight: bold; text-decoration: none;">seperti </del>[[<del style="font-weight: bold; text-decoration: none;">C5a</del>]] dan [[<del style="font-weight: bold; text-decoration: none;">C5b</del>]].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Perforin <ins style="font-weight: bold; text-decoration: none;">dapat ditemukan pada [[granula|granul]] [[sel T]] CD8 dan [[sel NK]]. Setelah proses </ins>[[<ins style="font-weight: bold; text-decoration: none;">degranulasi</ins>]]<ins style="font-weight: bold; text-decoration: none;">, sekresi perforin akan tersisipkan pada </ins>[[<ins style="font-weight: bold; text-decoration: none;">membran sel</ins>]] dan <ins style="font-weight: bold; text-decoration: none;">membentuk sebuah lubang. Bagian perforin yang menancap pada membran tersebut adalah domain </ins>[[<ins style="font-weight: bold; text-decoration: none;">MACPF</ins>]].<ins style="font-weight: bold; text-decoration: none;"><ref>Tschopp J, Masson D, Stanley KK. [https://archive.org/details/sim_nature-uk_1986-08-28_322_6082/page/831 Structural/functional similarity between proteins involved in complement- and cytotoxic T-lymphocyte-mediated cytolysis]. ''Nature''. 1986. Vol. 322 (6082). hlm. 831–4. doi:10.1038/322831a0.</ref></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Perforin <del style="font-weight: bold; text-decoration: none;">juga berinteraksi </del>dengan [[<del style="font-weight: bold; text-decoration: none;">Kalretikulin</del>]].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Perforin <ins style="font-weight: bold; text-decoration: none;">bersinergi </ins>dengan <ins style="font-weight: bold; text-decoration: none;">''membrane-attack complex'' (MAC) yang dilakukan protein </ins>[[<ins style="font-weight: bold; text-decoration: none;">komplemen</ins>]] <ins style="font-weight: bold; text-decoration: none;">seperti [[C5a]] dan [[C5b]].<ref>Janeway, Charles A.; Travers, Paul; Walport, Mark; Shlomchik, Mark. [http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=imm&part=A161 Immunobiology]. Garland Science. 2001</ins>. <ins style="font-weight: bold; text-decoration: none;">Section 2-5</ref></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">== Rujukan ==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Perforin juga berinteraksi dengan [[Kalretikulin]].<ref>C Andrin. ''Interaction between a Ca2+-binding protein calreticulin and perforin, a component of the cytotoxic T-cell granules''. ''Biochemistry''. 1998. Vol. 37 (29). hlm. 10386–94. doi:10.1021/bi980595z.</ref></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Referensi ==</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><references /></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Sumber dan atribusi ==</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del style="font-weight: bold; text-decoration: none;">Sumber </del>dan <del style="font-weight: bold; text-decoration: none;">atribusi ==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title</ins>=<ins style="font-weight: bold; text-decoration: none;">Perforin&oldid</ins>=<ins style="font-weight: bold; text-decoration: none;">29576720 Wikipedia bahasa Indonesia], revisi 29576720 (2026-08-14T11:17:15Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Gambar pada artikel ini bersumber dari Wikimedia Commons </ins>dan <ins style="font-weight: bold; text-decoration: none;">mengikuti ketentuan lisensi masing-masing berkas. Mohon gunakan konten dan media secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Perforin&oldid=29576720 Wikipedia bahasa Indonesia], revisi 29576720 (2026</del>-<del style="font-weight: bold; text-decoration: none;">08</del>-<del style="font-weight: bold; text-decoration: none;">14T11:17:15Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi</del>-<del style="font-weight: bold; text-decoration: none;">BerbagiSerupa (CC BY</del>-<del style="font-weight: bold; text-decoration: none;">SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><!</ins>-- <ins style="font-weight: bold; text-decoration: none;">WIKI_UNISSULA_PRESENTATION_V4 </ins>--<ins style="font-weight: bold; text-decoration: none;">></ins></div></td></tr>
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https://wiki.unissula.ac.id/index.php?title=Perforin&diff=26369&oldid=prev
Maintenance script: Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 29576720; atribusi sumber disertakan.
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<p>Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 29576720; atribusi sumber disertakan.</p>
<p><b>Halaman baru</b></p><div>'''Perforin''' () adalah [[sitokin]] berupa [[protein]] yang diekspresikan oleh [[gen]] PRF1.<br />
<br />
Perforin dapat ditemukan pada [[granula|granul]] [[sel T]] CD8 dan [[sel NK]]. Setelah proses [[degranulasi]], sekresi perforin akan tersisipkan pada [[membran sel]] dan membentuk sebuah lubang. Bagian perforin yang menancap pada membran tersebut adalah domain [[MACPF]].<br />
<br />
Perforin bersinergi dengan ''membrane-attack complex'' (MAC) yang dilakukan protein [[komplemen]] seperti [[C5a]] dan [[C5b]].<br />
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Perforin juga berinteraksi dengan [[Kalretikulin]].<br />
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== Rujukan ==<br />
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== Sumber dan atribusi ==<br />
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Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Perforin&oldid=29576720 Wikipedia bahasa Indonesia], revisi 29576720 (2026-08-14T11:17:15Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div>
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