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Prekursor monoamina - Riwayat revisi
2026-09-15T20:40:59Z
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Maintenance script: Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi
2026-08-29T14:03:04Z
<p>Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Revisi sebelumnya</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revisi per 29 Agustus 2026 14.03</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Baris 1:</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Istilah '''prekursor monoamina''' merujuk pada </del>[[<del style="font-weight: bold; text-decoration: none;">prekursor (kimia)|prekursor]] monoamina dan neurotransmiter monoamina dalam tubuh. [[Asam amino]] L-[[triptofan]] dan </del>L-<del style="font-weight: bold; text-decoration: none;">5</del>-<del style="font-weight: bold; text-decoration: none;">hidroksitriptofan (5</del>-<del style="font-weight: bold; text-decoration: none;">HTP atau oksitriptan) adalah prekursor [[serotonin]] dan [[melatonin]], sedangkan asam amino </del>L-<del style="font-weight: bold; text-decoration: none;">[[fenilalanina]], L</del>-<del style="font-weight: bold; text-decoration: none;">[[tirosina]], dan </del>L-<del style="font-weight: bold; text-decoration: none;">DOPA ([[levodopa</del>]]<del style="font-weight: bold; text-decoration: none;">) adalah prekursor [[dopamin]], epinefrin ([[adrenalin]]), dan norepinefrin ([[noradrenalin]]).</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[<ins style="font-weight: bold; text-decoration: none;">File:</ins>L-<ins style="font-weight: bold; text-decoration: none;">Tryptophan_</ins>-<ins style="font-weight: bold; text-decoration: none;">_L</ins>-<ins style="font-weight: bold; text-decoration: none;">Tryptophan.svg|thumb|right|280px|</ins>L-<ins style="font-weight: bold; text-decoration: none;">Tryptophan </ins>- L-<ins style="font-weight: bold; text-decoration: none;">Tryptophan</ins>]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Pemberian </del>prekursor monoamina <del style="font-weight: bold; text-decoration: none;">dapat meningkatkan kadar </del>neurotransmiter monoamina dalam tubuh <del style="font-weight: bold; text-decoration: none;">dan otak</del>. <del style="font-weight: bold; text-decoration: none;">Prekursor monoamina dapat digunakan dalam kombinasi dengan </del>[[<del style="font-weight: bold; text-decoration: none;">penghambat dekarboksilase asam </del>amino L <del style="font-weight: bold; text-decoration: none;">aromatik|penghambat dekarboksilase </del>asam amino L <del style="font-weight: bold; text-decoration: none;">aromatik</del>]] [[<del style="font-weight: bold; text-decoration: none;">obat selektif perifer|selektif perifer</del>]] <del style="font-weight: bold; text-decoration: none;">(penghambat AAAD</del>, <del style="font-weight: bold; text-decoration: none;">juga dikenal sebagai penghambat dekarboksilase </del>DOPA (<del style="font-weight: bold; text-decoration: none;">DDC)) seperti </del>[[<del style="font-weight: bold; text-decoration: none;">karbidopa</del>]] <del style="font-weight: bold; text-decoration: none;">dan </del>[[<del style="font-weight: bold; text-decoration: none;">benserazida</del>]] <del style="font-weight: bold; text-decoration: none;">untuk membatasi metabolisme dan aktivasi di perifer. </del>[[<del style="font-weight: bold; text-decoration: none;">Karbidopa/levodopa</del>]] dan [[<del style="font-weight: bold; text-decoration: none;">levodopa/benserazida</del>]] <del style="font-weight: bold; text-decoration: none;">digunakan untuk meningkatkan kadar dopamin otak dalam pengobatan </del>[[<del style="font-weight: bold; text-decoration: none;">penyakit Parkinson</del>]]<del style="font-weight: bold; text-decoration: none;">. Karbidopa</del>/<del style="font-weight: bold; text-decoration: none;">oksitriptan (EVX</del>-<del style="font-weight: bold; text-decoration: none;">101), yang meningkatkan kadar serotonin otak, sedang dikembangkan sebagai </del>[[<del style="font-weight: bold; text-decoration: none;">antidepresan</del>]] <del style="font-weight: bold; text-decoration: none;">untuk kemungkinan penggunaan dalam pengobatan depresi.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Istilah '''</ins>prekursor monoamina<ins style="font-weight: bold; text-decoration: none;">''' merujuk pada [[prekursor (kimia)|prekursor]] monoamina dan </ins>neurotransmiter monoamina dalam tubuh. [[<ins style="font-weight: bold; text-decoration: none;">Asam </ins>amino<ins style="font-weight: bold; text-decoration: none;">]] L-[[triptofan]] dan </ins>L<ins style="font-weight: bold; text-decoration: none;">-5-hidroksitriptofan (5-HTP atau oksitriptan) adalah prekursor [[serotonin]] dan [[melatonin]], sedangkan </ins>asam amino L<ins style="font-weight: bold; text-decoration: none;">-[[fenilalanina</ins>]]<ins style="font-weight: bold; text-decoration: none;">, L-</ins>[[<ins style="font-weight: bold; text-decoration: none;">tirosina</ins>]], <ins style="font-weight: bold; text-decoration: none;">dan L-</ins>DOPA ([[<ins style="font-weight: bold; text-decoration: none;">levodopa</ins>]]<ins style="font-weight: bold; text-decoration: none;">) adalah prekursor </ins>[[<ins style="font-weight: bold; text-decoration: none;">dopamin</ins>]]<ins style="font-weight: bold; text-decoration: none;">, epinefrin (</ins>[[<ins style="font-weight: bold; text-decoration: none;">adrenalin</ins>]]<ins style="font-weight: bold; text-decoration: none;">), </ins>dan <ins style="font-weight: bold; text-decoration: none;">norepinefrin (</ins>[[<ins style="font-weight: bold; text-decoration: none;">noradrenalin</ins>]]<ins style="font-weight: bold; text-decoration: none;">).<sup class="reference" id="wu-cite-1">[</ins>[<ins style="font-weight: bold; text-decoration: none;">#wu-ref-1|</ins>[<ins style="font-weight: bold; text-decoration: none;">1</ins>]]<ins style="font-weight: bold; text-decoration: none;">]<</ins>/<ins style="font-weight: bold; text-decoration: none;">sup><sup class="reference" id="wu-cite</ins>-<ins style="font-weight: bold; text-decoration: none;">2">[</ins>[<ins style="font-weight: bold; text-decoration: none;">#wu-ref-2|</ins>[<ins style="font-weight: bold; text-decoration: none;">2]</ins>]]<ins style="font-weight: bold; text-decoration: none;"></sup></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Droksidopa (L-DOPS) adalah prekursor sintetis atau [[bakal obat]] norepinefrin yang digunakan secara oral dalam pengobatan jenis [[tekanan darah rendah|hipotensi]] tertentu dan kondisi lainnya. Dipivefrina adalah prekursor sintetis atau bakal obat epinefrin yang digunakan sebagai obat mata.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Pemberian prekursor monoamina dapat meningkatkan kadar neurotransmiter monoamina dalam tubuh dan otak.<sup class="reference" id="wu-cite-3">[[#wu-ref-3|[3]]]</sup> Prekursor monoamina dapat digunakan dalam kombinasi dengan [[penghambat dekarboksilase asam amino L aromatik|penghambat dekarboksilase asam amino L aromatik]] [[obat selektif perifer|selektif perifer]] (penghambat AAAD, juga dikenal sebagai penghambat dekarboksilase DOPA (DDC)) seperti [[karbidopa]] dan [[benserazida]] untuk membatasi metabolisme dan aktivasi di perifer. [[Karbidopa/levodopa]] dan [[levodopa/benserazida]] digunakan untuk meningkatkan kadar dopamin otak dalam pengobatan [[penyakit Parkinson]].<sup class="reference" id="wu-cite-4">[[#wu-ref-4|[4]]]</sup> Karbidopa/oksitriptan (EVX-101), yang meningkatkan kadar serotonin otak, sedang dikembangkan sebagai [[antidepresan]] untuk kemungkinan penggunaan dalam pengobatan depresi.<sup class="reference" id="wu-cite-5">[[#wu-ref-5|[5]]]</sup><sup class="reference" id="wu-cite-6">[[#wu-ref-6|[6]]]</sup></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Droksidopa (L-DOPS) adalah prekursor sintetis atau [[bakal obat]] norepinefrin yang digunakan secara oral dalam pengobatan jenis [[tekanan darah rendah|hipotensi]] tertentu dan kondisi lainnya.<ins style="font-weight: bold; text-decoration: none;"><sup class="reference" id="wu-cite-7">[[#wu-ref-7|[7]]]</sup><sup class="reference" id="wu-cite-8">[[#wu-ref-8|[8]]]</sup> </ins>Dipivefrina adalah prekursor sintetis atau bakal obat epinefrin yang digunakan sebagai obat mata.<ins style="font-weight: bold; text-decoration: none;"><sup class="reference" id="wu-cite-9">[[#wu-ref-9|[9]]]</sup></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Lihat juga==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Lihat juga==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[Bakal obat neurotransmiter]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[Bakal obat neurotransmiter]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>==Referensi==</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>== Referensi ==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><ol class="references wiki-unissula-manual-references"></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><li id="wu-ref-1">Ingrid Kohlstadt. [https://books.google.com/books?id=KDxUfc-rEs8C&pg=PA472 Food and Nutrients in Disease Management]. CRC Press. 19 April 2016. ISBN 9781420067637. <span class="mw-cite-backlink">[[#wu-cite-1|↑]]</span></li></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><li id="wu-ref-2">John Fernandes. [https://books.google.com/books?id=-chW0k3aFXMC&pg=PA364 Inborn Metabolic Diseases: Diagnosis and Treatment]. Springer. 22 November 2006. ISBN 9783540287858. <span class="mw-cite-backlink">[[#wu-cite-2|↑]]</span></li></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><li id="wu-ref-3">John Fernandes. [https://books.google.com/books?id=-chW0k3aFXMC&pg=PA364 Inborn Metabolic Diseases: Diagnosis and Treatment]. Springer. 22 November 2006. ISBN 9783540287858. <span class="mw-cite-backlink">[[#wu-cite-3|↑]]</span></li></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><li id="wu-ref-4">''Levodopa in the treatment of Parkinson's disease: current status and new developments''. ''J Parkinsons Dis''. January 2013. Vol. 3 (3). hlm. 255–69. doi:10.3233/JPD-130186. <span class="mw-cite-backlink">[[#wu-cite-4|↑]]</span></li></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><li id="wu-ref-5">[https://escholarship.org/uc/item/58h866d5 Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan]. ''Pharmacol Ther''. March 2006. Vol. 109 (3). hlm. 325–338. doi:10.1016/j.pharmthera.2005.06.004. <span class="mw-cite-backlink">[[#wu-cite-5|↑]]</span></li></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><li id="wu-ref-6">Sumber pada Wikipedia bahasa Indonesia. <span class="mw-cite-backlink">[[#wu-cite-6|↑]]</span></li></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><li id="wu-ref-7">''L-Dihydroxyphenylserine (L-DOPS): a norepinephrine prodrug''. ''Cardiovasc Drug Rev''. 2006. Vol. 24 (3–4). hlm. 189–203. doi:10.1111/j.1527-3466.2006.00189.x. <span class="mw-cite-backlink">[[#wu-cite-7|↑]]</span></li></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><li id="wu-ref-8">[https://par.nsf.gov/servlets/purl/10332412 Phenols in Pharmaceuticals: Analysis of a Recurring Motif]. ''J Med Chem''. May 2022. Vol. 65 (10). hlm. 7044–7072. doi:10.1021/acs.jmedchem.2c00223. <span class="mw-cite-backlink">[[#wu-cite-8|↑]]</span></li></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><li id="wu-ref-9">[https://par.nsf.gov/servlets/purl/10332412 Phenols in Pharmaceuticals: Analysis of a Recurring Motif]. ''J Med Chem''. May 2022. Vol. 65 (10). hlm. 7044–7072. doi:10.1021/acs.jmedchem.2c00223. <span class="mw-cite-backlink">[[#wu-cite-9|↑]]</span></li></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ol></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Sumber dan atribusi ==</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del style="font-weight: bold; text-decoration: none;">Sumber </del>dan <del style="font-weight: bold; text-decoration: none;">atribusi ==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title</ins>=<ins style="font-weight: bold; text-decoration: none;">Prekursor+monoamina&oldid</ins>=<ins style="font-weight: bold; text-decoration: none;">28968528 Wikipedia bahasa Indonesia], revisi 28968528 (2026-02-16T14:19:43Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Gambar pada artikel ini bersumber dari Wikimedia Commons </ins>dan <ins style="font-weight: bold; text-decoration: none;">mengikuti ketentuan lisensi masing-masing berkas. Mohon gunakan konten dan media secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Prekursor+monoamina&oldid=28968528 Wikipedia bahasa Indonesia], revisi 28968528 (2026</del>-<del style="font-weight: bold; text-decoration: none;">02</del>-<del style="font-weight: bold; text-decoration: none;">16T14:19:43Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi</del>-<del style="font-weight: bold; text-decoration: none;">BerbagiSerupa (CC BY</del>-<del style="font-weight: bold; text-decoration: none;">SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><!</ins>-- <ins style="font-weight: bold; text-decoration: none;">WIKI_UNISSULA_PRESENTATION_V4 </ins>--<ins style="font-weight: bold; text-decoration: none;">></ins></div></td></tr>
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https://wiki.unissula.ac.id/index.php?title=Prekursor_monoamina&diff=26224&oldid=prev
Maintenance script: Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 28968528; atribusi sumber disertakan.
2026-08-29T13:27:25Z
<p>Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 28968528; atribusi sumber disertakan.</p>
<p><b>Halaman baru</b></p><div>Istilah '''prekursor monoamina''' merujuk pada [[prekursor (kimia)|prekursor]] monoamina dan neurotransmiter monoamina dalam tubuh. [[Asam amino]] L-[[triptofan]] dan L-5-hidroksitriptofan (5-HTP atau oksitriptan) adalah prekursor [[serotonin]] dan [[melatonin]], sedangkan asam amino L-[[fenilalanina]], L-[[tirosina]], dan L-DOPA ([[levodopa]]) adalah prekursor [[dopamin]], epinefrin ([[adrenalin]]), dan norepinefrin ([[noradrenalin]]).<br />
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Pemberian prekursor monoamina dapat meningkatkan kadar neurotransmiter monoamina dalam tubuh dan otak. Prekursor monoamina dapat digunakan dalam kombinasi dengan [[penghambat dekarboksilase asam amino L aromatik|penghambat dekarboksilase asam amino L aromatik]] [[obat selektif perifer|selektif perifer]] (penghambat AAAD, juga dikenal sebagai penghambat dekarboksilase DOPA (DDC)) seperti [[karbidopa]] dan [[benserazida]] untuk membatasi metabolisme dan aktivasi di perifer. [[Karbidopa/levodopa]] dan [[levodopa/benserazida]] digunakan untuk meningkatkan kadar dopamin otak dalam pengobatan [[penyakit Parkinson]]. Karbidopa/oksitriptan (EVX-101), yang meningkatkan kadar serotonin otak, sedang dikembangkan sebagai [[antidepresan]] untuk kemungkinan penggunaan dalam pengobatan depresi.<br />
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Droksidopa (L-DOPS) adalah prekursor sintetis atau [[bakal obat]] norepinefrin yang digunakan secara oral dalam pengobatan jenis [[tekanan darah rendah|hipotensi]] tertentu dan kondisi lainnya. Dipivefrina adalah prekursor sintetis atau bakal obat epinefrin yang digunakan sebagai obat mata.<br />
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==Lihat juga==<br />
* [[Bakal obat neurotransmiter]]<br />
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==Referensi==<br />
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== Sumber dan atribusi ==<br />
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Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Prekursor+monoamina&oldid=28968528 Wikipedia bahasa Indonesia], revisi 28968528 (2026-02-16T14:19:43Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div>
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