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Protimosin-alfa - Riwayat revisi
2026-09-16T04:09:29Z
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https://wiki.unissula.ac.id/index.php?title=Protimosin-alfa&diff=26861&oldid=prev
Maintenance script: Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi
2026-08-29T14:13:12Z
<p>Presentation V4: sitasi, referensi, Math, Wikimedia Commons, dan atribusi</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Revisi sebelumnya</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revisi per 29 Agustus 2026 14.13</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Baris 1:</td>
<td colspan="2" class="diff-lineno">Baris 1:</td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">'''Protimosin-α''' () adalah prekursor dari </del>[[<del style="font-weight: bold; text-decoration: none;">hormon]] dan substansi serupa hormon yang di[[sekresi]] oleh [[kelenjar]] [[timus]], dan mempunyai panjang 113 [[asam amino</del>|<del style="font-weight: bold; text-decoration: none;">AA</del>]] <del style="font-weight: bold; text-decoration: none;">pada [[tikus]].</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[<ins style="font-weight: bold; text-decoration: none;">File:2l9i_thymosin_alpha-1.png|thumb|right|280px</ins>|<ins style="font-weight: bold; text-decoration: none;">2l9i thymosin alpha-1</ins>]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">ProT memiliki derajat keasaman yang sangat tinggi dan terdistribusi sangat merata pada [[sel </del>(<del style="font-weight: bold; text-decoration: none;">biologi</del>)<del style="font-weight: bold; text-decoration: none;">|sel]] </del>[[<del style="font-weight: bold; text-decoration: none;">mamalia</del>]]<del style="font-weight: bold; text-decoration: none;">. Semenjak diketemukan pada tahun 1984, peran ProT masih terus menjadi perdebatan. Awalnya, ProT dianggap sebagai faktor timik dengan fungsi hormonal </del>yang <del style="font-weight: bold; text-decoration: none;">berperan dalam mematangkan </del>[[<del style="font-weight: bold; text-decoration: none;">sel T</del>]]<del style="font-weight: bold; text-decoration: none;">. Irisan ProT berupa Timosin-α1 dan Timosin fraksi 5 merupakan </del>[[<del style="font-weight: bold; text-decoration: none;">protein</del>]] <del style="font-weight: bold; text-decoration: none;">yang menginduksi diferensiasi </del>[[<del style="font-weight: bold; text-decoration: none;">sel T</del>]]<del style="font-weight: bold; text-decoration: none;">. Analisis molekular </del>dan <del style="font-weight: bold; text-decoration: none;">seluler lebih lanjut memberikan bukti-bukti bahwa ProT tergolong </del>[[asam <del style="font-weight: bold; text-decoration: none;">nukleat</del>]] <del style="font-weight: bold; text-decoration: none;">yang diperlukan dalam proses proliferasi, dan memiliki kapasitas untuk membuka lipatan fiber dari </del>[[<del style="font-weight: bold; text-decoration: none;">kromatin</del>]] <del style="font-weight: bold; text-decoration: none;">melalui interaksi dengan </del>[<del style="font-weight: bold; text-decoration: none;">[histon</del>]<del style="font-weight: bold; text-decoration: none;">] H1</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">'''Protimosin-α''' </ins>() <ins style="font-weight: bold; text-decoration: none;">adalah prekursor dari </ins>[[<ins style="font-weight: bold; text-decoration: none;">hormon</ins>]] <ins style="font-weight: bold; text-decoration: none;">dan substansi serupa hormon </ins>yang <ins style="font-weight: bold; text-decoration: none;">di</ins>[[<ins style="font-weight: bold; text-decoration: none;">sekresi</ins>]] <ins style="font-weight: bold; text-decoration: none;">oleh </ins>[[<ins style="font-weight: bold; text-decoration: none;">kelenjar</ins>]] [[<ins style="font-weight: bold; text-decoration: none;">timus</ins>]]<ins style="font-weight: bold; text-decoration: none;">, </ins>dan <ins style="font-weight: bold; text-decoration: none;">mempunyai panjang 113 </ins>[[asam <ins style="font-weight: bold; text-decoration: none;">amino|AA</ins>]] <ins style="font-weight: bold; text-decoration: none;">pada </ins>[[<ins style="font-weight: bold; text-decoration: none;">tikus</ins>]]<ins style="font-weight: bold; text-decoration: none;">.<ref></ins>[<ins style="font-weight: bold; text-decoration: none;">http://www.ncbi.nlm.nih.gov/omim/188390 PROTHYMOSIN, ALPHA; PTMA</ins>]. <ins style="font-weight: bold; text-decoration: none;">''OMIM''.</ref></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">== Rujukan ==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">ProT memiliki derajat keasaman yang sangat tinggi dan terdistribusi sangat merata pada [[sel (biologi)|sel]] [[mamalia]]. Semenjak diketemukan pada tahun 1984, peran ProT masih terus menjadi perdebatan.<ref>[http://www.ncbi.nlm.nih.gov/pubmed/10605816 Prothymosin alpha]. ''Department of Cell Biology and Physiology, Washington University School of Medicine; Segade F, Gómez-Márquez J''.</ref> Awalnya, ProT dianggap sebagai faktor timik dengan fungsi hormonal yang berperan dalam mematangkan [[sel T]]. Irisan ProT berupa Timosin-α1 dan Timosin fraksi 5 merupakan [[protein]] yang menginduksi diferensiasi [[sel T]].<ref>[http://www.ncbi.nlm.nih.gov/pubmed/2599716 Characterization of the immunoregulatory properties of thymosin alpha 1 on interleukin-2 production and interleukin-2 receptor expression in normal human lymphocytes]. ''Department of Medicine, George Washington University School of Medicine; Sztein MB, Serrate SA''.</ref> Analisis molekular dan seluler lebih lanjut memberikan bukti-bukti bahwa ProT tergolong [[asam nukleat]] yang diperlukan dalam proses proliferasi, dan memiliki kapasitas untuk membuka lipatan fiber dari [[kromatin]] melalui interaksi dengan [[histon]] H1.<ref>[http://www.ncbi.nlm.nih.gov/pubmed/9628907 Prothymosin alpha modulates the interaction of histone H1 with chromatin]. ''Laboratory of Biological Chemistry, University of Ioannina; Karetsou Z, Sandaltzopoulos R, Frangou-Lazaridis M, Lai CY, Tsolas O, Becker PB, Papamarcaki T''.</ref></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
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<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><references /></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Sumber dan atribusi ==</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del style="font-weight: bold; text-decoration: none;">Sumber </del>dan <del style="font-weight: bold; text-decoration: none;">atribusi ==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title</ins>=<ins style="font-weight: bold; text-decoration: none;">Protimosin-alfa&oldid</ins>=<ins style="font-weight: bold; text-decoration: none;">27780235 Wikipedia bahasa Indonesia], revisi 27780235 (2025-09-05T03:04:20Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Gambar pada artikel ini bersumber dari Wikimedia Commons </ins>dan <ins style="font-weight: bold; text-decoration: none;">mengikuti ketentuan lisensi masing-masing berkas. Mohon gunakan konten dan media secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Protimosin</del>-<del style="font-weight: bold; text-decoration: none;">alfa&oldid=27780235 Wikipedia bahasa Indonesia], revisi 27780235 (2025</del>-<del style="font-weight: bold; text-decoration: none;">09</del>-<del style="font-weight: bold; text-decoration: none;">05T03:04:20Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi</del>-<del style="font-weight: bold; text-decoration: none;">BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><!</ins>-- <ins style="font-weight: bold; text-decoration: none;">WIKI_UNISSULA_PRESENTATION_V4 </ins>--<ins style="font-weight: bold; text-decoration: none;">></ins></div></td></tr>
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Maintenance script: Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 27780235; atribusi sumber disertakan.
2026-08-29T13:52:09Z
<p>Impor teks terkontrol dari Wikipedia bahasa Indonesia; revisi 27780235; atribusi sumber disertakan.</p>
<p><b>Halaman baru</b></p><div>'''Protimosin-α''' () adalah prekursor dari [[hormon]] dan substansi serupa hormon yang di[[sekresi]] oleh [[kelenjar]] [[timus]], dan mempunyai panjang 113 [[asam amino|AA]] pada [[tikus]].<br />
<br />
ProT memiliki derajat keasaman yang sangat tinggi dan terdistribusi sangat merata pada [[sel (biologi)|sel]] [[mamalia]]. Semenjak diketemukan pada tahun 1984, peran ProT masih terus menjadi perdebatan. Awalnya, ProT dianggap sebagai faktor timik dengan fungsi hormonal yang berperan dalam mematangkan [[sel T]]. Irisan ProT berupa Timosin-α1 dan Timosin fraksi 5 merupakan [[protein]] yang menginduksi diferensiasi [[sel T]]. Analisis molekular dan seluler lebih lanjut memberikan bukti-bukti bahwa ProT tergolong [[asam nukleat]] yang diperlukan dalam proses proliferasi, dan memiliki kapasitas untuk membuka lipatan fiber dari [[kromatin]] melalui interaksi dengan [[histon]] H1.<br />
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== Rujukan ==<br />
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== Sumber dan atribusi ==<br />
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Konten artikel ini diadaptasi dari [https://id.wikipedia.org/w/index.php?title=Protimosin-alfa&oldid=27780235 Wikipedia bahasa Indonesia], revisi 27780235 (2025-09-05T03:04:20Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.</div>
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