Interleukin 5

IL5 Crystal Structure.rsh

Interleukin 5, disingkat IL-5 () adalah sitokina sekresi sel T_H^[1] yang berperan dalam perkembangan dan diferensiasi sel B dan eosinofil.^[2]

Peningkatan rasio IL-5 dilaporkan terkait dengan asma dan sindrom hipereosinofilik,^[3] seperti eosinofilia.^[4] Tingginya rasio IL-5 juga ditemukan pada penderita penyakit Graves dan tiroiditis Hashimoto.^[5]

Referensi

↑ Naive helper T cells from BCG-vaccinated volunteers produce IFN-gamma and IL-5 to mycobacterial antigen-pulsed dendritic cells. Department of Immunology and Infectious Biology, University of Lodz; Kowalewicz-Kulbat M, Kaźmierczak D, Donevski S, Biet F, Pestel J, Rudnicka W.
↑ 1: IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]. Entrez Gene.
↑ 1: IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]. Entrez Gene.
↑ TARC and IL-5 expression correlates with tissue eosinophilia in peripheral T-cell lymphomas. Department of Pathology, CHU of Liège, University of Liège; Thielen C, Radermacher V, Trimeche M, Roufosse F, Goldman M, Boniver J, de Leval L.
↑ The role of T-lymphocyte subsets and interleukin-5 blood levels among Indian subjects with autoimmune thyroid disease. Defence Bio-engineering and Electromedical Laboratory; Gopalakrishnan S, Sen S, Adhikari JS, Chugh PK, Sekhri T, Rajan S.

Sumber dan atribusi

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[1] Naive helper T cells from BCG-vaccinated volunteers produce IFN-gamma and IL-5 to mycobacterial antigen-pulsed dendritic cells. Department of Immunology and Infectious Biology, University of Lodz; Kowalewicz-Kulbat M, Kaźmierczak D, Donevski S, Biet F, Pestel J, Rudnicka W.

[2] 1: IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]. Entrez Gene.

[3] 1: IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]. Entrez Gene.

[4] TARC and IL-5 expression correlates with tissue eosinophilia in peripheral T-cell lymphomas. Department of Pathology, CHU of Liège, University of Liège; Thielen C, Radermacher V, Trimeche M, Roufosse F, Goldman M, Boniver J, de Leval L.

[5] The role of T-lymphocyte subsets and interleukin-5 blood levels among Indian subjects with autoimmune thyroid disease. Defence Bio-engineering and Electromedical Laboratory; Gopalakrishnan S, Sen S, Adhikari JS, Chugh PK, Sekhri T, Rajan S.

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