Protein FLICE-i

Protein FLICE-i () adalah faktor transkripsi dengan berkas genetik CFLAR pada kromosom 2 lokasi 2q33-q34,^[1] yang banyak terdapat pada jaringan otot dan jaringan limfoid,^[2] sebagai regulator apoptosis.

Overekspresi FLIP dapat melindungi sel tumor dari mekanisme apoptosis.^[3]

Referensi

↑ CFLAR CASP8 and FADD-like apoptosis regulator [ Homo sapiens ]. Entrez Gene.
↑ Inhibition of death receptor signals by cellular FLIP. Institute of Biochemistry, Lausanne branch, University of Lausanne; Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J.
↑ The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer. Cancer Research UK Institute for Cancer Studies, Division of Cancer Studies, Department of Pathology, The Medical School, University of Birmingham; Dutton A, Young LS, Murray PG.

Sumber dan atribusi

Konten artikel ini diadaptasi dari Wikipedia bahasa Indonesia, revisi 16236195 (2019-11-29T13:07:16Z), yang tersedia berdasarkan lisensi Creative Commons Atribusi-BerbagiSerupa (CC BY-SA). Mohon gunakan konten ini secara bijak serta sesuai dengan ketentuan lisensi yang berlaku.

[1] CFLAR CASP8 and FADD-like apoptosis regulator [ Homo sapiens ]. Entrez Gene.

[2] Inhibition of death receptor signals by cellular FLIP. Institute of Biochemistry, Lausanne branch, University of Lausanne; Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J.

[3] The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer. Cancer Research UK Institute for Cancer Studies, Division of Cancer Studies, Department of Pathology, The Medical School, University of Birmingham; Dutton A, Young LS, Murray PG.

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